Pudendal neuralgia
Pudendal nerve entrapment, pudendal neuralgia, and pudendal neuropathy — all these terms refer to the same condition that causes unbearable pain and discomfort. The pathology develops when the pudendal nerve — one of the main pelvic nerves — is damaged or compressed (entrapped).
There is still no consensus in the medical community regarding the classification of the above-mentioned terms. For example, the terms “pudendal neuralgia” and “pudendal neuropathy” are closely related and are sometimes used interchangeably. The term “nerve entrapment” is more specific — it refers to neuralgia or neuropathy caused specifically by compressive factors, such as pressure from ligaments, abnormally enlarged muscles, and so on.
A muscular man with a serious expression walks into the office. His urologist referred him to me, although the patient had hoped it would all be resolved with a short course of antibiotics:
— “I just got back from Latin America, was literally trekking through the jungle. We lived in tents, bathed in natural ponds, almost alongside crocodiles. I thought I’d picked up an infection, but the tests came back clean. No discharge either.”
— “Please describe your symptoms again.”
— “It’s an intense pain in the most intimate area and nearby. It’s like a sharp shooting pain. Sometimes it turns dull, but it never really goes away. It can intensify within a split second if I move suddenly.”
— “Pelvic pain syndrome can occur with many conditions. When did you first feel it?”
— “After a barbell workout. I do weightlifting. Never had anything like this before — it came on suddenly, if you can say that.”
— “That suggests a higher risk of pudendal neuralgia. Do you experience itching? Where exactly is the pain located? How would you describe it?”
— “It feels like — sorry for being blunt — like something’s been inserted into my penis, and it’s hot. The pain is in the perineum, sometimes radiates to the buttocks. Touching the area makes it worse… But, to be honest,” — the patient hesitates, “my sensations might be a little off right now. I tried to ease the pain by putting an ice pack on my scrotum and think I may have given myself a cold burn.”
This kind of thing happens occasionally. A patient overwhelmed by constant pain and unable to see a doctor right away will try to relieve the discomfort with whatever means are at hand. Sometimes they overdo it.
— “Doctor, is there a surgery for this?”
— “Technically, yes. But it’s too early to talk about that. First, we need to pinpoint exactly what's causing your pain. Second, surgery is only done when there are clear indications. It's a complex procedure, and we need to be certain that it can actually help.”
— “So, it might not be pudendal nerve entrapment after all? Could it be something easier to treat?” — there's a flicker of hope in the man’s eyes.
— “I can’t say for sure yet, but none of your symptoms rule out that possibility. We need more accurate diagnostics. I’ll refer you for an ultrasound and electroneuromyography. These aren’t 100% definitive, but they’ll give us a general picture. A third method is a nerve block. We'll inject an anesthetic into the painful area, and if that brings relief, we can confidently say the pudendal nerve is indeed affected.”
— “But what do I do right now? I’m going home after this, I’ve got work tomorrow — I have to live with this somehow.”
— “For now, let’s consider starting medication and possibly combining it with local anesthesia methods. You won’t need that ice pack anymore, of course. There are lidocaine patches that work well for many patients, and there are also medications that have proven effective.”
— “But every movement hurts! I’ve taken so many pills — anti-inflammatories, painkillers — nothing works.”
— “The treatment should bring some relief once we begin. But you’ll also need to make a few lifestyle adjustments. For example, get a cushion with a hole in the middle so sitting doesn’t put pressure on the nerve. That will ease your condition and help you work at a computer more comfortably. In the meantime, we’ll tailor your medication, run the tests, and analyze the results. Sound good? Then we’ll reassess your condition and decide on next steps.”
Signs and Symptoms of the Condition
The primary symptom of pudendal neuropathy is pain that can persist for years in one or more areas innervated by the pudendal nerve or its branches. This includes the central lower pelvic region:
- the rectum and anal area;
- the perineum;
- the penis and scrotum in men;
- the clitoral and vulvar area in women.
Pain can be either unilateral or bilateral, occurring locally or affecting all regions at once — the course of the condition is highly individual. The pain may be present in any position but often lessens when lying down or standing. Typically, symptoms worsen when the patient is sitting, especially for extended periods.
Pudendal neuralgia is a condition in which the pain differs from typical muscular pain.
Patients describe the pain as:
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burning;
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stinging;
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stabbing;
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shooting;
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comparable in intensity and nature to toothache;
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cutting, like a knife;
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twisting;
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irritating, and so on.
Many vivid and intense descriptions are given, including colorful expressions such as “the sensation of a hot poker in the penis.” In addition, neuropathy can cause difficulties with urination, defecation, and sexual intercourse — the process of carrying out natural bodily functions is inseparably linked with excruciating pain. Erectile dysfunction, pathological arousal without genuine sexual desire, or, conversely, loss of sensation, may also occur.
How Pudendal Nerve Entrapment Occurs
The pudendal (genital) nerve emerges from the sacral plexus, enters the gluteal region through the lower part of the greater sciatic foramen, passes through the pelvis, and branches into:
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rectal branch;
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anal branch;
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perineal branch;
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clitoral-penile branch.
Compression causes entrapment, which leads to pathological nerve reactions such as scarring, thickening, and inflammation. The nerve is most commonly compressed in two locations:
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where it passes beneath the bone-ligament junction (80% of cases),
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and in the Alcock’s canal (20% of cases).
Since the nerve naturally narrows at these points, any increase in its diameter results in constant pressure. This creates a vicious cycle: the more the nerve is compressed, the greater the swelling, which in turn increases the compression again.
Causes of Pudendal Neuropathy
There are many causes that can lead to the development of neuralgia in the genital and surrounding areas. Among them are:
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mechanical injuries and trauma resulting from childbirth, sports-related falls, and similar incidents;
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autoimmune diseases;
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inflammations and infections (for example, genital herpes);
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traumatic surgical procedures;
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anatomical predisposition;
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prolonged sitting during work or long trips, and others.
At risk are professional cyclists; in the medical community, there is even an informal term called "cyclist syndrome." The pelvic position during cycling increases the likelihood of pudendal nerve entrapment, so athletes often require treatment for neuralgia. Additionally, sports that involve frequent hip flexion can provoke the condition, as during training the muscles or ligaments surrounding the nerve may enlarge.
There is a hypothesis that patients ultimately diagnosed with pudendal neuropathy had an initial predisposition and simultaneously engaged in activities that triggered the condition. From this perspective, consider two people with a predisposition: one who took up weightlifting and one who did not. In the first person’s life, a triggering event occurred, leading to the development of the pathology, while the second remained healthy.
Many patients undergoing treatment for neuropathy report recalling an event that triggered their subsequent pain. In women, pudendal neuralgia often begins after childbirth, while in men, it commonly follows a blow or fall. Common patient recollections include:
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falling onto the buttocks (for example, from a bicycle);
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a car accident;
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surgery on the sacrum or pelvic organs.
What to Do If You Experience Symptoms of Genital Neuropathy
Treatment of the condition is impossible without the involvement of a doctor. On patient forums, there are sections like “Ask a Doctor” and videos of exercises to reduce pain from pudendal nerve neuropathy, but these are only partial measures that may sometimes provide temporary relief.
It is very important to establish an accurate diagnosis. One of the methods is Electroneuromyography (ENMG), a study of nerve conduction and signal transmission speed.
A radical treatment method is surgery, which can help eliminate pain and allow a return to an active lifestyle. However, it is preceded by a complex, multi-stage diagnostic process aimed not only at identifying symptoms but also at ruling out other conditions that could cause similar pain.
There are no specific tests for neuropathy, but the so-called Nantes criteria have been developed—a list of signs indicating the nature of the pathology.
The doctor will propose surgical intervention if a precise diagnosis is established. The success rate of the operation is up to 83%. In some cases, residual effects may persist afterward — in any case, the situation requires medical supervision for at least several more years.